Synthetic and semi-synthetic strategies to study ubiquitin signaling
نویسندگان
چکیده
منابع مشابه
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Ubiquitination is of great importance as the post-translational modification of proteins with ubiquitin, or ubiquitin chains, facilitates a number of vital cellular processes. Herein we present a facile method of preparing various ubiquitin conjugates under mild conditions using michael acceptors based on dibromo-maleimides and dibromo-pyridazinediones.
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ژورنال
عنوان ژورنال: Current Opinion in Structural Biology
سال: 2016
ISSN: 0959-440X
DOI: 10.1016/j.sbi.2016.05.022